Projects/Case Studies

Collaboration Opportunities

If you have an interest in, and would like to collaborate on any of the following areas, please contact us:

Engineering and Robotics

Project 1:  Magnets and surgical instruments for abdominal surgery

Project 2:  Learning the behaviours of surgeons in keyhole surgery

Project 3:  Virtual reality systems to train surgeons and new users

Project 4:  3D mesh which allows the surgeon to draw regions of interest so that only the areas of interest are operated on.

Project 5:  Augmented surgery to avoid entanglement issues.

Project 6:  Using haptics for measuring pressure forces during surgery

Project 7:  Minimising tissue trauma due to graspers or instruments

Project 8:  Understanding tissue and how it reacts when a device comes into contact with it and how that is dissipated in terms of trauma.

Colorectal

Project 1:  Developing realistic in silico and in vivo models that more precisely recapitulate the tumour and its micro/macro environment, to enable comprehensive dissection of the relevant mechanisms governing the transition from normal colorectum to the different malignant stages of the disease.

Project 2:  Develop and share appropriate model systems that mimic different premalignant/malignant stages of colorectal cancer.

Project 3:  Developing precise pathological assessment of colorectal cancer.

Project 4: Impact of Anastomosis Type on Complications Following Right hemicolectomy

Pathology

Project 1:  The role of the gut microbiome and how it can be exploited to improve colorectal cancer disease outcomes.

Project 2: The use of liquid biopsies

Project 3:  Increasing the accuracy and reproducibility of morphological prognostic factors.

Project 4:  Digital pathology, translational bioinformatics and machine learning to underpin algorithm development for risk prediction/disease stratification.

Project 5:  Translation of discovery research findings on the molecular pathogenesis of IBD-associated neoplasia to improve utility and cost-effectiveness of screening approaches at the population level.

Project 6:  Standardised approaches for pathology specimen analysis.

Clinical Trials

Project 1:  Design and implement prospective high-quality pan-population studies of risk factors for colorectal cancer, with robust clinical/pathological data, supporting blood and tissue samples, to inform a population-based assessment of risk.

Project 2:  Delivery of high-quality robust long-term studies that identify the appropriate level of intervention including dose, duration, timing, feasibility and acceptability as well as a clinically relevant outcomes.

Project 3:  Methods to ensure optimal evaluation of new surgical and radiotherapy-related devices and procedures to demonstrate appropriately robust clinical and cost-effective outcomes.

Health Economics

Project 1:  Embedding research randomised controlled trials in FIT-based screening programmes to explore the optimal FIT threshold and/or the role of flexible sigmoidoscopy, incorporating risk adjustment algorithms.

Cross Cutting

Project 1:  Novel technologies/interventions that have the potential to improve curative outcomes for cancer.

Project 2:  The use of the XCM BIOLOGIC® Tissue Matrix for abdominal wall hernia repair and other soft tissue reconstruction applications